Prevention of ulceration, amputation, and reduction of hospitalization: outcomes of a prospective multicenter trial of tibial neurolysis in patients with diabetic neuropathy.

نویسندگان

  • A Lee Dellon
  • Vickie L Muse
  • D Scott Nickerson
  • Thomas Akre
  • Sharon R Anderson
  • Steve L Barrett
  • Kent R Biddinger
  • Peter J Bregman
  • Bryan P Bullard
  • Damien M Dauphinee
  • James M DeJesus
  • Ramon A DeJesus
  • Ivica Ducic
  • Jeffery Dunkerly
  • Michael R Galina
  • Virginia Hung
  • Dolf R Ichtertz
  • Michael F Kutka
  • Richard P Jacoby
  • J Barry Johnson
  • David W Mader
  • Christopher T Maloney
  • Peter J Mancuso
  • R Craig Martin
  • Rick F Martin
  • Brian A McDowel
  • Vito J Rizzo
  • Michael Rose
  • Gedge D Rosson
  • Bruce B Shafiroff
  • Jerome K Steck
  • Raymond G Stolarski
  • Patrick Swier
  • Tatiana A Wellens-Bruschayt
  • Bronwyn Wilke
  • Eric H Williams
  • Michael A Wood
  • William A Wood
  • Michael P Younes
  • Fuat Yuksel
چکیده

This is the first multicenter prospective study of outcomes of tibial neurolysis in diabetics with neuropathy and chronic compression of the tibial nerve in the tarsal tunnels. A total of 38 surgeons enrolled 628 patients using the same technique for diagnosis of compression, neurolysis of four medial ankle tunnels, and objective outcomes: ulceration, amputation, and hospitalization for foot infection. Contralateral limb tibial neurolysis occurred in 211 patients for a total of 839 operated limbs. Kaplan-Meier proportional hazards were used for analysis. New ulcerations occurred in 2 (0.2%) of 782 patients with no previous ulceration history, recurrent ulcerations in 2 (3.8%) of 57 patients with a previous ulcer history, and amputations in 1 (0.2%) of 839 at risk limbs. Admission to the hospital for foot infections was 0.6%. In patients with diabetic neuropathy and chronic tibial nerve compression, neurolysis can result in prevention of ulceration and amputation, and decrease in hospitalization for foot infection.

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عنوان ژورنال:
  • Journal of reconstructive microsurgery

دوره 28 4  شماره 

صفحات  -

تاریخ انتشار 2012